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Synthesis of Antimalarial Compounds and Their Intermediates

Jezik AngleščinaAngleščina
Knjiga Mehka
Knjiga Synthesis of Antimalarial Compounds and Their Intermediates Yashumati Ratan
Koda Libristo: 06842449
Založba VDM Verlag, maj 2011
The resistance of malaria parasites to widely used drugs prompted an upsurge in the development of n... Celoten opis
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The resistance of malaria parasites to widely used drugs prompted an upsurge in the development of new drugs with novel mechanism of action, and re- evaluation of the existing drugs to overcome the resistance problem. A number of new potential target pathways have already been identified and efforts to develop lead compounds for these putative targets hopefully will allow treatment of malaria infections in a uniform sustained way. Considerable research efforts were directed in the areas of chloroquine drug resistance reversal agents. Careful development of some bisquinolines, which are free of toxic side effect, 4-anilinoquinolines and modified chloroquine analogs may be helpful to obtain drug candidates that inhibit the growth of chloroquine sensitive and resistant parasites. In the past several years, new structural classes of antimalarial agents, target based antimalarial agents, iron chelators have made some interesting and promising lead molecules available for further optimization to provide compounds for clinical development.

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O knjigi

Polni naslov Synthesis of Antimalarial Compounds and Their Intermediates
Jezik Angleščina
Vezava Knjiga - Mehka
Datum izida 2011
Število strani 108
EAN 9783639354416
ISBN 3639354419
Koda Libristo 06842449
Založba VDM Verlag
Teža 168
Mere 152 x 229 x 7
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