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Splines And Compartment Models: An Introduction

Name: Splines And Compartment Models: An Introduction
Brand: World Scientific Publishing Co Pte Ltd
SKU: 05071060
Price: 125.35 EUR
Availability: InStock
Author: Karl-Ernst Biebler
ISBN: 9789814522229

Karl-Ernst Biebler

Michael Wodny

Jezik

Angleščina

Knjiga Trda

Koda Libristo: 05071060

Založba World Scientific Publishing Co Pte Ltd, september 2013

This book presents methods of mathematical modeling from two points of view. Splines provide a gener... Celoten opis

Koda Libristo: 05071060

303 b

125.35 €

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This book presents methods of mathematical modeling from two points of view. Splines provide a general approach while compartment models serve as examples for context related to modeling. The preconditions and characteristics of the developed mathematical models as well as the conditions surrounding data collection and model fit are taken into account. The substantial statements of this book are mathematically proven. The results are ready for application with examples and related program codes given. In this book, splines are algebraically developed such that the reader or user can easily understand and vary the numerical construction of the different kinds of spline functions. The classical compartment models of the pharmacokinetics are systematically analyzed and connected with lifetime distributions. As such, parameter estimation and model fit can be treated statistically with a varied minimum chi-square method. This method is applicable for single kinetics and also allows the calculation of average kinetics.