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This book provides readers with a comprehensive review of fundamentals as well as the current state-of-the-art in research and technology on quantum computing. The authors provide design paradigms of quantum computing, including developing a full stack from quantum algorithms to quantum chips. Advances in quantum computing hardware, software, and algorithms as well as contributions on the transformative research needed to guide quantum computing performance toward practical and sustainable operations are discussed. Further, circuits and systems targeting novel and existing applications of quantum computing to fields such as quantum chemistry, linear algebra, scientific applications, aerospace, material science, machine learning, etc. are also be covered.