Next Generation Sequencing (NGS) Technology in DNA Analysis

Next Generation Sequencing (NGS) Technology in DNA Analysis explains and summarizes NGS technological applications in the field of forensic DNA analysis. The book covers the shift from capillary electrophoresis (CE) to NGS platforms; the fundamentals of NGS technologies, application, and advancements. The book is organized into three parts. Part 1 provides an overview of NGS Technology and forensic science providing an overview of NGS technologies, information on processing biological samples for forensic analysis, sequence analysis and data analysis software and the analysis of NGS data. Part 2 explores the useful applications of NGS based forensic DNA analysis. Part 3 covers the validations and interpretation guidelines of NGS workflows. With chapter contributions from an internationally array of experts and the inclusion of practical case studies, Next Generation Sequencing (NGS) Technology in DNA Analysis is a useful reference for academics and researchers in genetics, biotechnology, bioinformatics, biology, and medicine as well as forensic DNA scientists and practitioners who aim to learn, use, apply and validate NGS-based technologies. Describes the fundamentals of NGS and its advancements for forensic applications Explains the shift from capillary electrophoresis (CE) based technique to Next Generation Sequencing (NGS) technologies Includes of case studies related to NGS and DNA fingerprinting Explores the future use and applications of NGS technologies