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Myeloid-Derived Suppressor Cells
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Myeloid-Derived Suppressor Cells, Volume 184 in the Methods in Cell Biology series includes comprehensive and detailed protocols to assess the critical role of myeloid-derived suppressor cells (MDSCs), an immature, heterogenous cell population from the myeloid lineage with a potent immunosuppressive activity in a variety of diseases. This volume presents twelve interesting protocols that address the isolation of MDSCs in murine models, the detection of mouse and human MDSCs by flow cytometry, T-cell proliferation assays, isolation of MDSC-derived exosomes and their immunosuppressive function, characterization of lysosomal lipase in MDSCs, detection of MDSC-derived nitric oxide, and other in vivo and ex vivo assays. Provides the authority and expertise of leading researchers in myeloid-derived suppressor cellsIncludes comprehensive and detailed protocols to assess the detrimental role of myeloid-derived suppressor cellsPresents the latest release in the Methods in Cell Biology series
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