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Systematically summarizes and discusses the basic concepts and latest updates of mesenchymal stem cells (MSCs) in the past 60 years, as well as the latest progress of clinical translational research and regulatory policy at home and abroad, which will be of great practical significance for promoting and guiding the future development of stem cell production and regenerative medicine. Systematically introduces the latest updates on Mesenchymal stem cells (MSCs), which will help readers have a systematic understanding of MSCs Summarize the knowledge of MSC-based cytotherapy in clinical practice, which will benefit the clinicians and help them design MSC-relevant clinical trials Introduce the newly developed concepts of MSC-based tissue engineering
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