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Ethosomes: Unique Elastic Vesicular Carrier
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Ethosomes are ethanolic phospholipid-based elastic vesicles which have a potential as novel topical and transdermal drug delivery systems, and which can act as carriers for various medicaments. Ethosomes have gained importance in the area of research, because of their intensified skin permeation, better delivery of drug and increased drug entrapment efficiency. These systems are more efficient in delivering substances to the skin because of the presence of ethanol, which provides a net negative charge on the surface, which helps to avoid aggregation of vesicles due to electrostatic repulsion than either conventional liposomes or hydroalcoholic solutions in terms of quantity and depth. Applications in different conditions enhance the utility of ethosomal formulations. Hence, this book highlights different aspects of ethosomes that distinguishes this vesicular carrier from other lipid nanocarriers.
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