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DNA Hydroxymethylation in Non-coding Repeat Expansion Disorders

Name: DNA Hydroxymethylation in Non-coding Repeat Expansion Disorders
Brand: Scholars Press
SKU: 16756760
Price: 60.44 EUR
Availability: InStock
Author: Rustam Esanov
ISBN: 9783330653122

Rustam Esanov

Jezik

Angleščina

Knjiga Mehka

Koda Libristo: 16756760

Založba Scholars Press, november 2016

My research is focused on the repeat expansion disorders, a family of disorders that result from the... Celoten opis

Koda Libristo: 16756760

146 b

60.44 €

Na zalogi pri dobavitelju Odposlali bomo v 5-8 dneh

Do 30 dni za vračilo

My research is focused on the repeat expansion disorders, a family of disorders that result from the repetitive microsatellite sequence within the gene. In particular, this thesis investigates two non-coding repeat expansion disorders: C9orf72-associated Amyotrophic Lateral Sclerosis (C9-ALS) and the Fragile X Syndrome (FXS). Our group was the first to report the presence of 5-hydroxymethylcytosine, a novel epigenetic mark and active DNA demethylation intermediate, at the expanded loci of patients with C9-ALS and FXS.