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Developments in T Cell Based Cancer Immunotherapies

Jezik AngleščinaAngleščina
Knjiga Mehka
Knjiga Developments in T Cell Based Cancer Immunotherapies Paolo A. Ascierto
Koda Libristo: 21072437
Založba Birkhauser, marec 2019
This volume illustrates the salient aspects of cancer biology relevant to the successful implementat... Celoten opis
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145.12 €
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This volume illustrates the salient aspects of cancer biology relevant to the successful implementation of immunotherapy. Topics include enhancement of antigen-specific immune responses by anti-cancer vaccines, modulation of the function of T cells within the tumor microenvironment, and the effects of genetic, epigenetic, developmental, and environmental determinants on T cell function. Other topics covered include the ex vivo expansion of T or other immune cells and their genetic modification or reprogramming to increase their ability to survive and expand when adoptively transferred back to the patients. Specific attention is devoted to the genetic manipulation of T cells through the introduction of re-directed T cell receptors, chimeric antibody receptors, and other genetic manipulation aimed at improving their effectiveness as anti-cancer agents. Furthermore, the revolutionary role of checkpoint inhibitors and their potential in combination with other immunotherapeutic approaches or with standard chemo and radiation therapy are extensively discussed.

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O knjigi

Polni naslov Developments in T Cell Based Cancer Immunotherapies
Jezik Angleščina
Vezava Knjiga - Mehka
Datum izida 2019
Število strani 305
EAN 9783319793306
Koda Libristo 21072437
Založba Birkhauser
Teža 670
Mere 155 x 235 x 14
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